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Focus fire refers to attacking a specific target with many champions, with the intent to destroy it that turn before it heals, retreats, or otherwise recovers.

This is a common tactic used against enemy champions because destroyed champions can't recover after they are destroyed. It's also especially common against champions which are more destructive when partially destroyed, such as those with Enrage or Blood Frenzy, or those which are able to retreat or heal, such those with Escape or Regeneration.

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