|3||3||Target champion within 5 spaces is Cleansed (all negative conditions are removed) and then is healed for 5 HP. May target self.|
Cleanse as an ability removes negative condtions, but it is common for cleansing to come from a spell (such as Cleansing Storm), ability (such as Purified or a rune such as Vial of Holy Water), or a by-product of something else (such as Intensify).
There are numerous negative conditions in the game, and if a champion is cleansed, all of them are removed.
Note some undesirable conditions mention they are not cleansible for balance reasons, such as Pacified. Also notice abilities are not cleansible. This includes Lumbering and Short-Lived, even if given from another rune or ability.